Paul Thompson's Research Publications

Animated Simulation of Brain Tumor Growth

by Paul Thompson



Distortions in Brain Architecture Induced by Tumor Tissue:
Probability Maps for Major Sulci in Both Hemispheres.


Color-coded probability maps quantify the impact of two focal metastatic tumors (illustrated in red) on the supracallosal, parieto-occipital, and anterior and posterior calcarine sulci in both hemispheres.

The animation shows a time-varying linear blend of:

(1) the anatomic configuration of the brain tumor patient, with
(2) the average anatomic representation for a group of normal subjects.

Probability maps indicate the severity of structural abnormality in intermediate surfaces (red colors: abnormal; blue colors: normal), relative to an encoding of normal anatomic variability.

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